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产品目录

p150 glued/DCTN1抗体图片
产品货号:
Z35167
中文名称:
p150 glued/DCTN1抗体
英文名称:
Anti-p150 glued/DCTN1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-p150 glued/DCTN1 Antibody
指标别名DAP 150;DCTN1;DP 150;Dynactin subunit 1;HMN7B;P135;p150 glued
克隆性Monoclonal
检验物种human,mouse,bovine,swine
应用范围WB,IF
基因名称DCTN1
抗体来源Mouse
免疫原Purified recombinant human Dynactin 1 protein fragments expressed in E.coli.
计算分子量142KD
成分Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH7.4,150mM NaCl) with 0.2% sodium azide,50% glycerol.
纯化方式Affinity purification
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料Dynactin subunit 1 is a protein that in humans is encoded by the DCTN1 gene.This gene encodes the largest subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning,and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).
Uniprot IDQ14203
基因名全称Dynactin subunit 1
蛋白名全称Dynactin subunit 1
推荐稀释比WB 1:1000~1:2000
IF 1:100~1:500

相关搜索:p150 glued/DCTN1抗体p150 glued抗体DCTN1单抗Anti-p150 glued/DCTN1 Antibody
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