产品货号:
Z35167
中文名称:
p150 glued/DCTN1抗体
英文名称:
Anti-p150 glued/DCTN1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-p150 glued/DCTN1 Antibody |
指标别名 | DAP 150;DCTN1;DP 150;Dynactin subunit 1;HMN7B;P135;p150 glued |
克隆性 | Monoclonal |
检验物种 | human,mouse,bovine,swine |
应用范围 | WB,IF |
基因名称 | DCTN1 |
抗体来源 | Mouse |
免疫原 | Purified recombinant human Dynactin 1 protein fragments expressed in E.coli. |
计算分子量 | 142KD |
成分 | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH7.4,150mM NaCl) with 0.2% sodium azide,50% glycerol. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Dynactin subunit 1 is a protein that in humans is encoded by the DCTN1 gene.This gene encodes the largest subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning,and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). |
Uniprot ID | Q14203 |
基因名全称 | Dynactin subunit 1 |
蛋白名全称 | Dynactin subunit 1 |
推荐稀释比 | WB 1:1000~1:2000 IF 1:100~1:500 |
相关搜索:p150 glued/DCTN1抗体,p150 glued抗体,DCTN1单抗,Anti-p150 glued/DCTN1 Antibody